Smartphone app illuminates power consumption
A new application for the Android smartphone shows users and software developers how much power their applications are consuming. PowerTutor was developed by doctoral students and professors at the University of Michigan.
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Effect of real-time CPR feedback reported at resuscitation science symposium
The Resuscitation Outcomes Consortium is the largest clinical research network to study prehospital treatments for cardiac arrest in the United States and Canada. ROC conducted the first randomized study to assess if real-time audio-feedback, during the EMS prehospital course of care, would improve clinical outcome. Results of the study were presented on November 15 during the Resuscitation Science Symposium 2009 program.
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Saving the single cysteine: New antioxidant system found
We've all read studies about the health benefits of having a life partner. The same thing is true at the molecular level, where amino acids known as cysteines are much more vulnerable to damage when single than when paired up with other cysteines.
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High blood pressure easy to miss in children with kidney disease
Spot blood pressure readings in children with chronic kidney disease often fail to detect hypertension -- even during doctor's office visits -- increasing a child's risk for serious heart problems, according to research from Johns Hopkins Children's Center and other institutions. A report of the findings appears online in the Journal of American Society of Nephrology.
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It's a gas: New discovery may lead to heartier, high-yielding plants
In a research report in the November 2009 journal Genetics, scientists show how a family of genes (1-aminocyclopropane-1-carboxylate synthase, or ACS genes), in the weed Arabidopsis thaliana, are responsible for production of ethylene. This gas affects many aspects of plant development, and this information, which will be applicable to other plants, lays the foundation for future genetic manipulation that could make plants disease resistant, able to survive and thrive in difficult terrain, and increase yields.
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Genetic analysis helps dissect molecular basis of cardiovascular disease
Using highly precise measurements of plasma lipoprotein concentrations determined by nuclear magnetic resonance spectroscopy, researchers performed genetic association analysis across the whole genome among 17,296 women of European ancestry. This large scale analysis of the effects of common genetic variation on plasma lipoprotein profile, a critical component of cardiovascular risk, identified 43 genetic loci contributing to lipoprotein metabolism. The findings are published on Nov. 20 in the open-access journal PLoS Genetics.
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Older problem drinkers use more alcohol than do their younger counterparts
Older adults who have alcohol dependence problems drink significantly more than do younger adults who have similar problems, a new study has found. The findings suggest that older problem drinkers may have developed a tolerance for alcohol and need to drink even more than younger abusers to achieve the effects they seek.
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ESC to give talks on diabetes in 3 cities in China
As a result of successful events organized last year, a second Joint Scientific Forum, organized by the European Society of Cardiology and the European Association for the Study of Diabetes, two of the most respected professional medical organizations in Europe, will be held from Nov. 27-29 at three venues across China -- Beijing, Shanghai and Guangzhou.
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Just like old times: Generating RNA molecules in water
A key question in the origin of biological molecules like RNA and DNA is how they first came together billions of years ago from simple precursors. Now, in a study appearing in this week's JBC, researchers in Italy have reconstructed one of the earliest evolutionary steps yet: generating long chains of RNA from individual subunits using nothing but warm water.
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Rare pancreatic cancer patients may live longer when treated with radiation therapy
Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors, despite such tumors being commonly considered resistant to radiation therapy, according to a largest of its kind study in the Nov. 15 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology.
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Flax and yellow flowers can produce bioethanol
Surplus biomass from the production of flax sheaves, and generated from Brassica carinata, a yellow-flowered plant related to those which engulf fields in spring, can be used to produce bioethanol. This has been suggested by two studies carried out by Spanish and Dutch researchers and published in the journal Renewable and Sustainable Energy Reviews.
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Watching a cannibal galaxy dine
A new technique using near-infrared images, obtained with ESO's 3.58-meter New Technology Telescope, allows astronomers to see through the opaque dust lanes of the giant cannibal galaxy Centaurus A, unveiling its "last meal" in unprecedented detail -- a smaller spiral galaxy, currently twisted and warped. This amazing image also shows thousands of star clusters, strewn like glittering gems, churning inside Centaurus A.
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Delft breakthrough in bioethanol production from agricultural waste
With the introduction of a single bacterial gene into yeast, researchers from Delft University of Technology in the Netherlands achieved three improvements in bioethanol production from agricultural waste material: "More ethanol, less acetate and elimination of the major by-product glycerol." This week the invention was published in the scientific journal Applied and Environmental Microbiology.
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Possible link studied between childhood abuse and early cellular aging
Researchers from Brown University and Butler Hospital have determined that children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults. The findings are published online in the journal Biological Psychiatry. A print version of the article is also expected.
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Novel K-anonymity algorithm safeguards access to data
As electronic health records become more widely deployed, increasing amounts of health information are being collected. This data has many beneficial applications, such as research, public health, and health system planning. In a recent study, Dr. Khaled El Emam, the Canada Research Chair in Electronic Health Information at the CHEO Research Institute argues that there is a need for robust de-identification of patient data to avoid the negative impact that individual consent requirements have on studies using health record data for secondary purposes.
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Researchers begin to decipher metabolism of sexual assault drug
It's a naturally occurring brain chemical with an unwieldy name: 4-hydroxybutyrate (4-HB). Taken by mouth, it can be abused or used as a date-rape drug. Now, a team of Ohio and Michigan scientists have determined new routes by which 4-HB is metabolized by the body. "This is new and important information," said K. Michael Gibson, professor and chair of biological sciences at Michigan Technological University and a member of the research team.
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Ultrasound enhances noninvasive Down syndrome tests
The addition of a "genetic sonogram" maximizes the accuracy of noninvasive testing for Down syndrome, said a Baylor College of Medicine researcher who was lead author of a landmark study in the current issue of Obstetrics and Gynecology.
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Simple blood test could reduce repeat breast MRI scans in premenopausal women with irregular periods
A simple blood test corresponding to the follicular phase (days 3-14) of a normal menstrual cycle can aid in optimal scheduling of breast MRI exams in premenopausal women with irregular cycles -- possibly reducing the number of repeat scans and non-diagnostic tests patients experience and providing clearer images on which doctors make their recommendations, according to a study published in the December issue of the American Journal of Roentgenology.
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Projections of savings from health IT are baseless, Harvard researchers say
The increased computerization in US hospitals hasn't made them cheaper or more efficient, Harvard researchers say, although it may have modestly improved the quality of care for heart attacks. The findings contradict claims by President Obama and many lawmakers that health information technology, including electronic medical records, will save billions and help make reform affordable. The study uses data from the most extensive survey ever undertaken of hospital computerization.
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Therapy 32 times more cost effective at increasing happiness than money
Research by the University of Warwick and the University of Manchester finds that psychological therapy could be 32 times more cost effective at making you happy than simply obtaining more money. The research has obvious implications for large compensation awards in law courts but also has wider implications for general public health.
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UAB researchers discover antibody receptor identity, propose renaming immune-system gene
In what has eluded discovery for 30 years, scientists have identified a cellular receptor for the immune system's first-response antibody immunoglobulin M (IgM). The proposed name is the Fc mu receptor gene; it describes a key region of the IgM antibody that binds this receptor and fills in a crucial gap in understanding the science behind immune deficiencies and allergy diseases, says UAB researchers.
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UCSB physicists move 1 step closer to quantum computing
Physicists at UC Santa Barbara have made an important advance in electrically controlling quantum states of electrons, a step that could help in the development of quantum computing. The work is published online today on the Science Express Web site.
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New maize map to aid plant breeding efforts
A massive survey of genetic diversity in maize has produced a gene map that should pave the way to significant improvements in a plant that is a major source of food, fuel, animal feed and fiber around the world.
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Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. Their advance is a significant step toward crafting pharmaceuticals to fight these often life-endangering conditions in a new way.
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Shifting blame is socially contagious
Merely observing someone publicly blame an individual in an organization for a problem -- even when the target is innocent -- greatly increases the odds that the practice of blaming others will spread with the tenacity of the H1N1 flu.
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Nanotube defects equal better energy and storage systems
Most people would like to be able to charge their cell phones and other personal electronics quickly and not too often. A recent discovery made by UC San Diego engineers could lead to carbon nanotube-based supercapacitors that could do just this.
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New research into the mechanisms of gene regulation
A team of scientists led by Penn State's Ross Hardison has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth. They focused specifically on the complex process of producing red blood cells (erythrocytes). These cells contain large amounts of hemoglobin, a molecule essential for transporting oxygen throughout the body. The research results could help in the development of important new therapies to combat sickle-cell disease.
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Scripps research scientists find new link between insulin and core body temperature
A team led by scientists at the Scripps Research Institute have discovered a direct link between insulin -- a hormone long associated with metabolism and metabolic disorders such as diabetes -- and core body temperature. While much research has been conducted on insulin since its discovery in the 1920s, this is the first time the hormone has been connected to the fundamental process of temperature regulation.
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Preventing H1N1 spread to health care workers: Dilemma, debate and confusion
A commentary in the December issue of the Lancet Infectious Diseases brings to light the gaps in knowledge on the transmission of the influenza virus and its impact on decisions about how best to protect health care workers. Infectious diseases specialist Leonard Mermel, D.O., looks at the ongoing debate in light of the H1N1 pandemic, what past research tells us about the spread of influenza and what is missing in the debate.
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An atomic-level look at an HIV accomplice
Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of thwarting its infection-promoting activity.
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Tips from the Journals of the American Society for Microbiology
The following are tips from the Journals of the American Society for Microbiology: "Bacterially Produced Antifungal on Skin of Amphibians May Protect Against Lethal Fungus"; "New Therapy May be Effective Against Bacterial Infections and Sepsis"; and "Tooth-Binding Micelles Containing Antimicrobials May Provide Long-Term Cavity Protection."
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Why can't some people give up cocaine?
Drug dependency is a recurrent but treatable kind of addiction. However, not all people who are drug dependent progress in the same way once they stop taking drugs. A new study shows that, in the case of cocaine, a high score on the so-called "scale of craving," an antisocial personality type and previous heroin abuse are the factors most commonly involved in people falling back into the habit.
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First reconstitution of an epidermis from human embryonic stem cells
Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM Institute, published in the Lancet on Nov. 21, 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells.The goal is to one day be able to propose this unlimited resource of cells as an alternative treatment in particular for victims of third degree burns.
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Unknowlingly consuming endangered tuna
New DNA barcoding from the Sackler Institute for Comparative Genomics at the American Museum of Natural History shows that nearly a third of the tuna plated in sushi restaurants was bluefin -- even if it was not labeled bluefin on the menu.
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Technique finds gene regulatory sites without knowledge of regulators
A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. The technique has been experimentally validated in both the mouse genome and the fruit fly genome.
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Finding more in 'most'
Prof. Mira Ariel of Tel Aviv University has scientifically quanitifed the common interpretation of the word "most," finding it to be a measurement of 80 to 95 percent of a sample.
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Cigarettes harbor many pathogenic bacteria: Study
Cigarettes are widely contaminated with bacteria, including some known to cause disease in people, concludes a new study conducted by a University of Maryland environmental health researcher and microbial ecologists at the Ecole Centrale de Lyon in France.The research team describes the study as the first to show that "cigarettes themselves could be the direct source of exposure to a wide array of potentially pathogenic microbes among smokers and other people exposed to secondhand smoke."
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Surgery not linked to memory problems in older patients
For years, it has been widely assumed that older adults may experience memory loss and other cognitive problems following surgery. But a new study by School of Medicine researchers questions that assumption. In the 575 patients they studied, the investigators did not detect any long-term cognitive declines attributable to surgery.
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SMOS satellite instrument comes alive
The MIRAS instrument on ESA's SMOS satellite, launched earlier this month, has been switched on and is operating normally. MIRAS will map soil moisture and ocean salinity to improve our understanding of the role these two key variables play in regulating Earth's water cycle.
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Women can quit smoking and control weight gain
Many women don't quit smoking because they are afraid of gaining weight. That's because nicotine suppresses appetite and boosts a smoker's metabolism. But a new meta-analysis shows that women who quit smoking while receiving treatment for weight control are better able to control their weight gain and are more successful at quitting cigarettes. The finding disproves clinical guidelines that say trying to diet and quit smoking at the same time will sabotage efforts to ditch cigarettes.
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Reference genome of maize, most important US crop, is published by team co-led by CSHL scientists
A four-year, multi-institutional effort co-led by three Cold Spring Harbor Laboratory scientists culminated today in publication of a landmark series of papers in the journal Science revealing in unprecedented detail the DNA sequence of maize. Maize, or corn, as it is commonly called by North American consumers, is one of the world's most important plants and the most valuable agricultural crop grown in the United States, representing $47 billion in annual value.
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WPI researchers take aim at hard-to-treat fungal infections
Researchers at Worcester Polytechnic Institute have developed a new model system to study fungal infections. The system can be a powerful tool for screening potential drug targets for conditions like thrush, athlete's foot and vaginal yeast infections, which affect millions of people each year but are difficult to treat with existing medications. Using the new model, the researchers also identified a gene that may be a promising target for a new anti-fungal drug.
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Spanish biotechnology should focus on food and plant sectors to be more competitive
Spain and Latin American countries have an opportunity to take the lead in two small biotechnology sectors. Researchers from the University of Valencia, working together with the IDICHUS Foundation, have studied the productive fabric of the Spanish biotechnology industry. Their conclusion is that Spain's food and plant sectors have more clout than those in English-speaking countries.
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On the crest of wave energy
The ocean is a potentially vast source of electric power, yet as engineers test new technologies for capturing it, the devices are plagued by battering storms, limited efficiency and the need to be tethered to the seafloor.
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Let them eat snail
A nutritionist in Nigeria says that malnutrition and iron deficiency in schoolchildren could be reduced in her country by baking up snail pie. In a research paper to be published in the International Journal of Food Safety, Nutrition and Public Health, she explains snail is not only cheaper and more readily available than beef but contains more protein.
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Many pregnant women avoid HIV screening in Africa
"Prevention is the best cure" is a common expression, but what happens if preventative measures are not used? A large proportion of pregnant Ugandan women are going out of their way not to be HIV tested, increasing the risk of mother-to-child transmission.
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Milestone biodefense publication by Elsevier journal Vaccine
Last week during the Vaccines for Biothreats and Emerging and Neglected Diseases Symposium in Galveston Texas, the Elsevier journal Vaccine released a supplement dedicated to vaccines for biodefense. This publication provides a comprehensive, state-of-the-art overview on vaccines that have been developed against a diverse group of human and veterinary pathogens, including Bacillus anthracis, smallpox and blue tongue.
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Why Israeli rodents are more cautious than Jordanian ones
A series of studies carried out at the University of Haifa have found that rodent, reptile and ant lion species behave differently on either side of the Israel-Jordan border. "The border line, which is only a demarcation on the map, cannot contain these species, but the line does restrict humans and their diverse impact on nature," says Dr. Uri Shanas.
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Building the smart home wirelessly
Like the paperless office, the smart home has been a long time coming, but a report published in the International Journal of Internet Protocol Technology, suggests that radio tags coupled with mobile communications devices could soon provide seamless multimedia services to the home.
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ICT fails to accelerate drug approvals
Drug approvals are taking just as long as they ever did despite increased expenditure on new information technology at the Food and drug Administration. So says a statistical analysis of approval intervals from 1997 to 2006, published in the International Journal of Electronic Healthcare.
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Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items. Studies to date on phthalates have been inconsistent, with some linking exposure to these chemicals to hormone disruptions, birth defects, asthma and reproductive problems, while others have found no significant association between exposure and adverse effects.
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BoarCroc, RatCroc, DogCroc, DuckCroc and PancakeCroc
Fossils of five ancient crocs, including one with teeth like boar tusks and another with a snout like a duck's bill, have been discovered in the Sahara by National Geographic Explorer-in-Residence Paul Sereno. The five crocs, three of them newly named species, were part of the bizarre world of crocs that inhabited the southern land mass known as Gondwana some 100 million years ago.
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Active hearing process in mosquitoes
A mathematical model has explained some of the remarkable features of mosquito hearing. In particular, the male can hear the faintest beats of the female's wings and yet is not deafened by loud noises.
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Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin color. Research, published in BioMed Central's open-access journal Genome Biology, shows that Mexicans mate according to proportions of Native-American to European ancestry, while Puerto Ricans are more likely to settle down with someone carrying a similar mix of African and European genes.
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Laser therapy can aggravate skin cancer
High irradiances of low-level laser therapy should not be used over melanomas. Researchers writing in the open-access journal BMC Cancer studied the pain relieving, anti-inflammatory "cold laser," finding that it caused increased tumor growth in a mouse model of skin cancer.
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Braking news
Real-life particles released by car brake pads can harm lung cells in vitro. Researchers writing in BioMed Central's open-access journal Particle and Fibre Toxicology found that heavy braking, as in an emergency stop, caused the most damage, but normal breaking and even close proximity to a disengaged brake resulted in potentially dangerous cellular stress.
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U of M plant scientist uncovers clues to yield-boosting quirks of corn genome
The offspring of two inbred strains tend to be superior to both of their parents. Characterizing the gene-level variability that leads to this phenomenon, known as heterosis or hybrid vigor, could boost our ability to custom-tailor crops for specific traits, such as high protein content for human consumption or high glucose content for biomass fuel.
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